WTC rat has unique characteristics such as resistant to streptozotocin

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WTC rat has unique characteristics such as resistant to streptozotocin

Because we found that WTC rats might be resistant to streptozotocin (STZ), we have elucidated the mechanisms of resistant to the diabetogenic effects of STZ in the WTC rats. Dose response to STZ was evaluated with glucose levels. No significant changes in glucose level to STZ administration were observed in WTC rats. Insulin secretion by suppling glucose was preserved in WTC rats even after STZ...

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ژورنال

عنوان ژورنال: Biochemistry and Biophysics Reports

سال: 2016

ISSN: 2405-5808

DOI: 10.1016/j.bbrep.2016.08.024